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Chapter 12 - Water And Electrocytes.ppt - Chapter 12 Water...

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Chapter 12Water and Electrolytes
Water Distribution in the Body
Water Distribution in the BodyChanges during growth/agingTotal water decreasesExtracellular decreases, intracellularincreasesMaintenance of fluid balanceBeveragesLiquids in foodsSmall amount from metabolism (<10%)Total of about 2500 ml of fluid
Maintenance of Fluid BalanceOsmotic pressureOsmosisOsmolarity (volume)Osmolality (wt)Theoretical osmotic pressureSolute particles unable to pass freelythrough membraneEffective (actual) osmotic pressureNot affected by membranes permeable to asolute
Maintenance of Fluid BalanceEffective osmotic pressure of plasma andinterstitial fluid across the capillaryendothelium is caused by macromolecules, likeproteins, unable to pass thru the endotheliumPlasma protein concentration is higher thaninterstitial fluid, giving plasma a relatively highosmotic pressure, or water-attracting propertyColloids:Proteins and other macromoleculestoo large to cross the capillary endotheliumColloid osmotic pressure:The osmoticpressure attributed to them
Maintenance of Fluid BalanceFiltration forces– Hydrostatic pressure (Ppl)From heart pumping– ISF colloid osmotic pressure (IIisf)Weak due to low protein– Negative ISF hydrostatic pressure (Pisf)WeakThese forces countered by reabsorptionforce• Plasma osmotic pressure (IIpl) ~28 mm Hg
The Kidney’s RoleKidney AnatomyNephron = functionalunitBowman’s capsuleGlomerulus -capillary networkProximal convolutedtubuleLoop of HenleDistal convoluted tubuleCollecting duct
The Kidney’s RoleGlomerular filtrateUrine formation1. Filtrationthrough which theglomerular filtrate is formed2. Reabsorptionof selected filtratesubstances into the blood3. Secretionof materials into tubulesfrom surrounding capillaries
The Kidney’s RoleVasopressin(ADH or AVH)

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Term
Fall
Professor
KimberleeMatalon
Tags
pH, Sodium, Nephron, Bicarbonate

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