Lecture16-M50,51

Subtypesofschizophrenia understandingschizophrenia

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Unformatted text preview: nd social'problems. Subtypes'of'Schizophrenia Understanding'Schizophrenia What’s'going'on'in the'brain'in schizophrenia? Abnormal brain structure and activity Too'much'dopaminergic'receptor ac;va;on'help'to'explain'paranoia and'hallucina0ons;'it’s'like'taking amphetamine'overdoses'all'the'0me. Poor'coordina0on'of'neural'firing'in the'frontal'lobes'impairs'judgment and'self<control. The'thalamus'fires'during hallucina0ons'as'if'real'sensa0ons were'being'received. There'is'general'shrinking'of'many brain'areas'and'connec0ons'between them. Understanding'Schizophrenia Are'there'biological'risk'factors affec0ng'early'development? Biological Risk Factors Schizophrenia is somewhat more likely to develop when one or more of these factors is present: low'birth'weight maternal'diabetes older'paternal'age famine oxygen'depriva0on'during'delivery maternal'virus'during'mid<pregnancy impairing'brain'development Schizophrenia'is'more likely'to'develop'in babies'born: during'and'aUer'flu epidemics....
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