Chapter 11 - Transcription and Translation

Neither the idea of an rna world suggests that rna

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Unformatted text preview: liest molecule to both store information and catalyze reactions RNA splicing via splicesosomes could have evolved from self-splicing RNAs Synthesis and Processing of rRNAs 6 o o o o o o o o o o rRNA ribosomal RNA encoded in DNA as rDNA typically clustered in the genome in nondividing cells, rDNA are clustered in the nucleoli, where ribosomes are produced a eukaryotic cell may contain millions of ribosomes composed of proteins and rRNA note: svedbers unit (s) is the rate of sedimentation in centrifuge this is the unit ribosomes are measured in rRNA genes are arranged in tandem the rRNA transcription has a Christmas Tree pattern the promoter lies just upstream from the transcript initiation proteins that convert rRNA precursors into mature rRNA become associated with pre-rRNA during transcription the non transcribed spacer separates transcription units in a ribosomal gene cluster Processing of the rRNA Precursor o o o o o o o o o o o in humans, the large ribosomal subunit contains a 28S, 5.8 S and 5S rRNA the small ribosomal subunit contains 18S rRNA a single...
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