Molumby practice exam

Molumby practice exam - NAME SECTION INSTRUCTOR This exam...

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BIOS 101 Dr. Molumby NAME: Sample Exam SECTION #: INSTRUCTOR: This exam, an old final, is annotated with the correct answers, and also WHY I asked the question. Professors never just "write questions" on an exam, there is always a certain logic to them. The average on this exam was about 25/40. Multiple Choice Questions (worth 2 points each) Questions 1-2 refer to the following scenario: Imagine a population of 10,000 humans living on an isolated island. Every generation, an average of 100 individuals are born with cystic fibrosis, a genetic disease caused by a recessive allele (ie., individuals with the condition are cc, Cc individuals are unaffected, but carry the allele) Assume that the population is in Hardy-Weinberg equillibrium. (You can always count upon a question like this to see if you have mastered the math. That is why it always turns up on a problem set.) 1. What is the expected frequency of the dominant allele? A) .50 B) .10 C) .01 D) .90 E) .99 Find q from q2, which is 100(the carriers)/1000 or .01 So q=the square root of .01 or .10 p+q=1 so p=.90 This is an estimate, of course. 2. What is the expected frequency of the heterozygous genotype? A) .50 B) .18 C) .82 D) .90 E) .99 This is 2pq. Thus .90x.10x2=.18 3. Which evolutionary mechanism is smallest in large populations? (Basic memorization question, but this particular fact is central to understanding how genetic drift operates-if you do not know it, you do not understand genetic drift.) A) Mutation B) Migration C) Selection D) Nonrandom Mating E) Genetic Drift
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4. Which of the following is an assumption of the Hardy-Weinberg equillibrium. A) no mutation B) no migration C) infinite population size D) random mating E) all of the above (another straight memorization question, also another central point. If you do not remember this, you forgot a key point). For questions 5-6, match the description of the event with one of the following types of mutation. A) substitution B) insertion C) deletion D) duplication E) transposition 5. An A-T base pair is spontaneously replaced with a G-C base pair A 6. A retrovirus incorporates itself into the host’s genome, adding a 1,400 base pair sequence to the G6PDH gene of the target tissue. B These are both questions where you are asked to classify a scenario. I do a lot of that-it is one step up from memorization. In this case, you have to remember the types of mutation and classify the events. For Question 7-8, match the name of the scientist or philosopher with their contribution to the theory of Evolution. A) Plato B) Carolus Linneus C) Thomas Malthus D) Charles Lyell E) Georges Cuvier 7. Which scientist developed the idea that the geological processes in operation now are the same processes that occurred long ago? D
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Molumby practice exam - NAME SECTION INSTRUCTOR This exam...

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