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Tablet ppt.pdf - TABLETS Ideal College of Pharmacy and...

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TABLETSIdeal College ofPharmacy andResearchMrs. Suvarna BhadaneAsst. Professor
Tablets are compressed solid unit dosage formcontaining medicament or medicaments usuallycircular in shape and may be flat or biconvex.Tablet is defined as a compressed solid dosage formcontaining medicaments with or without excipients.Pharmaceutical tablets are solid, flat or biconvexdishes, unit dosage form, prepared by compressing adrugs or a mixture of drugs, with or without diluents.It is the most popular dosage form and 70% of the totalmedicines are dispensed in the form of Tablet
ADVANTAGES & DISADVANTAGESAdvantages of tablets:Easy to administered.Easy to dispense.More stable.Accuracy in dose.Bitter and nauseous substance can be easily dispensed.Light and compact.Economical.Sustained release product is possible by enteric coating.Disadvantages of tablets:Problem with compression to crystalline drug.Hygroscopic drugs are not suitable for compressed tablets.Drugs with low or poor water solubility, slow dissolution, may be difficult toformulate.Cost of production may be increase because of coating and encapsulation toremove bitter and unpleasant taste.Swallowing is difficult especially for children and ill (unconscious) patients
Ideal characteristics of tabletsA tablet must be strong and hard to withstand mechanical shock during manufacturing, packing, shipping,dispensing and use.The drug content of the tablet must be bioavailable that is, the tablet must be able to release its content in apredictable and reproducible manner.The tablet must be chemically and physically stable to maintain its chemical and physical attributes duringmanufacture, storage, and use.The tablet should have elegant product identity which is free from any tablet defect.Tablets must be uniform in weight and in drug content.
Different types of Tablets(A)Tablets ingested orally:1. Compressed tablet, e.g. Paracetamol tablet2. Multiple compressed tablet3. Repeat action tablet4. Delayed release tablet, e.g. Enteric coated Bisacodyl tablet5. Sugar coated tablet, e.g. Multivitamin tablet6. Film coated tablet, e.g. Metronidazole tablet7. Chewable tablet, e.g. Antacid tablet(B) Tablets used in oral cavity:1. Buccaltablet, e.g. Vitamin‐ctablet2.Sublingual tablet, e.g. Vicks Menthol tablet3.Troches or lozenges4.Dental cone
(c) Tablets administered by other route:1.Implantation tablet2.Vaginal tablet, e.g. Clotrimazole tablet(D) Tablets used to prepare solution:1.Effervescent tablet, e.g. Dispirin tablet (Aspirin)2.Dispensing tablet, e.g. Enzyme tablet (Digiplex)3.Hypodermic tablet4.Tablet triturates e.g. Enzyme tablet (Digiplex)
Preformulation AspectsTablet
DEFINATION OF PREFORMULATION:-“Preformulation is a branch of pharmacy which deals with the investigation of physical and chemical properties of a drugsubstance alone or when combined with excipients.

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Term
Fall
Professor
Karen Rucker
Tags
Tablet Press, Preformulation

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