PPT #3 - Lauralee Sherwood Chapter 8 Muscle Physiology Mark Paternostro West Virginia University Fig 7-5a p 250 Muscle pp 258-270 Comprises largest

PPT #3 - Lauralee Sherwood Chapter 8 Muscle Physiology Mark...

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Mark Paternostro • West Virginia University Lauralee Sherwood Chapter 8 Muscle Physiology
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Fig. 7-­‐5a, p. 250
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Muscle pp. 258-270 Comprises largest group of tissues in body 3 types of muscle Skeletal muscle Make up muscular system Cardiac muscle Found only in the heart Smooth muscle Appears throughout the body systems as components of hollow organs and tubes Classified in 2 different ways Striated or unstriated Voluntary or involuntary
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Fig. 8-1, p. 259
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Fig. 8-2a, p. 260 (a) Relationship of a whole muscle and a muscle fiber Connective tissue Muscle fiber (a single muscle cell) Tendon Muscle
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Fig. 8-2, p. 260 10-100 microns in diameter 750,000 microns (2.5 ft) in length Formed by fusion of myoblasts, therefore multiple nuclei in muscle cell
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Structure of Skeletal Muscle Myofibrils – Contractile elements of muscle fiber – Regular arrangement of thick and thin filaments Thick filaments myosin (protein) Thin filaments actin (protein) – Viewed microscopically myofibril displays alternating dark (the A bands ) and light bands (the I bands ) giving appearance of striations 12-18 nm diameter; 1.6 microns long 5-8 nm diameter 1 micron long NOTE: actin & myosin are often called contractile proteins ; however, neither contracts!!!!!!!!!!!!!!!!!
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Fig. 8-3a, p. 261 M line Sarcomere Z line Z line I band A band H zone (a) Electron micrograph of a myofibril
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Structure of Skeletal Muscle Sarcomere Functional unit of skeletal muscle Found between 2 Z lines (connects thin filaments of two adjoining sarcomeres) Regions of sarcomere A band Made up of thick filaments along with portions of thin filaments
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