2010 BME 259 Problem Set 3 - BME/ChE 259 Problem Set#3 Due...

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BME/ChE 259 Problem Set #3Due: September 30, 20101. Flow Chamber for Adhesion StudyA parallel plate flow chamber is being designed to study the adhesion of leukocytes to endothelium. The channel width is 2 cm. Determine channel heights that can be used to generate wall shear stresses (i.e. wyxhy2/as high as 20 dyne/cm2with flow rates less than 2 cm3/s. the viscosity of the tissue culture liquid medium is 0.0087 g/cm-s. 2. Two phase model of blood flow in small tubesOne explanation for the reduced hematocrit in a tube postulates that, in small capillary tubes (15 m RT150 m), blood separates into a cell-free plasma layer of thickness (typically 5 m) near the tube wall and a central core enriched in red blood cells (Figure

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