biol1201 Third_Exam_Study_Guide

biol1201 Third_Exam_Study_Guide - Examination 3 Study Guide...

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Examination 3 Study Guide Thursday April 3 at 6:00 PM in Campbell Auditorium Bring a number 2 pencil and your ID. 53 questions – the exam is worth 106 points Make sure you can do the genetics problems found under “Assignments” on Blackboard! The material in the textbook : Chapters 14, 15, 16 and 17. Focus on the material covered in lecture. 1. ABO/Rh blood groups - 10 questions Know the genetics/inheritance o Polygenic Inheritance Multiple genes contribute to a trait Examples: eye color, skin color, human height o Chromosomal Sex Determination XX (female), XY (male) XX, XO ZW (hen), ZZ (rooster) Be able to do problems on paternity exclusion o Genetics of ABO blood groups can be used to exclude paternity Multiple alleles, I^A, I^B, I^I, I^O o Could a man’s ABO genotype have produced gametes which would result in the child’s phenotype? o Man of blood type A - has phenotype A; Genotype I A - (Either I A I A or I A I; the genotype is not known ambiguously o Man of blood type AB- has phenotype AB; genotype must be I AB the genotype is known unambiguously o Man of blood type O - phenotype O, genotype must be ii; the genotype is known unambiguously o Child of blood type A- phenotype A; Genotype I A - (Either I A I A or I A i; the genotype is not known unambiguously; we know that one parent must contribute I A o Child of blood type AB- has phenotype AB; genotype must be I AB the genotype is known unambiguously; tells us one parent must contribute I A and one must contribute I B o Child of Blood type O- phenotype O, genotype must be ii; the genotype is known unambiguously; each parent must contribute an i allele Could a man of blood type A be excluded as the father of a type O child? NO- the man could be heterozygous (I A i) and could have contributed the i allele If the father was AB can he be excluded as the father of a type O child? YES- We know the man is heterozygous (I A I B ) and could not have contributed the I allele needed for the child
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Can a man of blood type O be excluded as the father of a type AB child? YES - We know that the man is homozygous (ii) and could not have contributed either the I A or the I B allele needed for the child Transfusions o What are the appropriate donors for transfusions? Recipient Blood Type (Phenotype) Donor Blood Type Genotype A A, O I A I A or I A i B B, O I B I B or I B i AB A, B, AB, O Universal recipient I A I B O O Universal donor ii Table 14.2: Determination of ABO Blood Group by Multiple Alleles
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2. seX-Linkage - 16 questions Figure 15.9 Figure 15.10
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Figure 15.11
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