quiz 9 - 2 mg B Indapamide 1.25 mg B Trichloromethiazide 4...

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Calcium Channel Blockers Drug Indications Oral? Injection? Dosage Verapramil HCl Hypertension, angina, PST IR, XL IV 40-240 mg Diltiazem HCl Angina, hypertension (XL only) IR, XL IV for fibrillation and PST NiFedipine Angina, hypertension (XL only) CC, XL 10-90 mg Nimodipine SAH SGC (liquid capsule) Nicardipine HCl Angina (IR only), hypertension IR, XL IV Isradipine HTN CR, IR Felodipine HTN XL Amlodipine Angina, hypertension Usually in combos 2.5-10 mg -not good for therapeutic interchange -indications differ for XL, SR, CR, IR, etc -HCTZ, portalidone: Cat B -only cardiologists and internal medicine docs should prescribe -P450’s metabolism. Inducers/inhibitors interact. Variability with each drug Thiazides Drug Oral? Injection? Pregnancy Notes Bendroflumethiazide 5 mg C Benthiazide 50 mg C Chlorothiazide (Diuril) 500 mg IV powder B original Hydrochlorothiazide (Hydrodiuril) 50 mg tablets, oral solution B Low dose, initial therapy Chlorothalidone (Hygroton) 50 mg B Low dose, initial therapy Hydroflumethiazide C Methyclothiazide C Polythiazide
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Unformatted text preview: 2 mg B Indapamide 1.25 mg B Trichloromethiazide 4 mg C-can cause hypokalemia. ACEIs cause hyperkalemia. Natural diuretics: -caffeine-ammonia Osmotic diuretics: treat intracranial pressure. Examples- mannitol, glycerine (IV/PO), urea IV. Beta blockers Drug Oral Injection Food to BA Notes Selective? Indications Propranolol HCl XL IV increase no MI, angina Off label: migraine Metoprolol 100 mg IV increase Toprol XL- succinate form. Generic AB yes MI, angina Timolol maleate 5-20 mg no Nadolol 40-80 mg decrease no angina Off label: Parkinsons tremors Atenolol 50-100 mg IV Cat D yes MI, angina Pindolol 5-10 mg decrease no Acebutolol HCl 200-400 mg yes Esmolol HCl IV only yes Supraventricular tachychardia No HTN Carteolol HCl 2.5-no Betaxolol 10-20 mg yes Penbutolol (sulfate salt) 20 mg no Bisoprolol fumarate 10 mg decrease yes sotalol 80-100 mg decrease Cat B no No HTN IV for acute MI and supraventricular tachychardia....
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This note was uploaded on 04/10/2008 for the course PHARM 30:725:320 taught by Professor Colaizzi during the Fall '07 term at Rutgers.

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quiz 9 - 2 mg B Indapamide 1.25 mg B Trichloromethiazide 4...

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