exam1a - BMB/MICRB 251 Exam 1 Use#2 pencil Answer all...

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BMB/MICRB 251 - September 23, 2004 - Exam 1 Use #2 pencil. Answer all questions on the enclosed optical read form. There is only one answer for each question. Read the question carefully and choose the BEST answer. Write your name and student I.D. number and fill in the corresponding oval. Be sure that your TEST FORM letter matches you EXAM FORM letter. This is EXAM FORM A There are 33 questions. The exam ends at 1:10 pm 1 Why do somatic cells lack telomerase? A. To help limit uncontrolled proliferation of cells, which die when telomere shortening after repeated cell divisions leads to loss of genetic information B. Since they are rapidly dividing cells they do not need to provide long term stabilizion of their telomeres C. To prevent uncontrolled transposition of retrotransposons D. Somatic cells lack telomeres and thus do not need telomerase. E. During cell division chromosomes condense, and this involves the binding of telomere binding proteins, which prevents the association of telomerase. Thus telomerase is not needed in somatic cells. 2 Which is NOT a property of enzymes A. The same enzyme can catalyze both the forward and reverse reaction. B. Enzymes alter the reaction equilibrium. C. Enzymes do not get used up in the reaction it catalyzes. D. Enzymes react with only specific substrates. E. Enzymes accelerate the rate of a reaction. 3 The movement of retrotransposons around the genome involves A. homologous recombination B. transposases C. packaging into retroviruses D. cutting and re-ligating a DNA intermediate E. an RNA intermediate 4 During DNA replication, what part of the growing polynucleotide chain makes a nucleophillic attack on an incoming nucleotide triphosphate A. base B. 2’ OH C. 3’ OH D. phosphate E. 5’ OH 5 Which biomolecule has both catalytic activity and an ability to store genetic information? A. DNA B. protein C. ATP D. RNA E. carbohydrates
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6 Which functional groups form ionic interactions with each other? A. methyl and phosphates B. phosphates and amines C. carboxylates and phosphates D. hydroxyl and hydroxyl E. sulfhydryl and hydroxyl 7 Which best describes the interior of a protein?
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  • Fall '04
  • Peterson
  • DNA

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