02 dnastruc

02 dnastruc - rays by crystals. • Franklin’s photo used...

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Topics for Today: Early Discoveries Science as a social  endeavor. What is the structure of  DNA? How is the structure of  DNA related to the  function of genetic  material? 
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Questions for the 1950’s A Paradox to explain: DNA has to copy itself exactly for each cell to function normally and natural selection to be explained. DNA must allow for changes (mutations and recombinations) in order for populations to evolve.
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Rosalind Franklin The Main Characters. .... Francis Crick Cavendish Labs Cambridge (under Bragg) Maurice Wilkins King’s College London (under Randall) James Watson
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Related Books and Links A Structure for Deoxyribose Nucleic Acid Nature VOL 171, page737, 1953 The Double Helix by James D. Watson A Reader's Guide to James D.Watson's The Double Helix Rosalind Franklin and DNA by Ann Sayre Science is a social endeavor!
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X-ray crystallography provides clues to the structure of DNA
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The analysis of the scattering or “diffraction” of x-
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Unformatted text preview: rays by crystals. • Franklin’s photo used to calculate structure of DNA. The Chemical Composition of DNA was known. Chargaff’s Rules: A=T and G=C G C Hydrogen Bonding existed between A and T and G and C Watson and Crick used these clues and model Watson and Crick used these clues and model building to construct a model of DNA building to construct a model of DNA . DNA is a double helix. . DNA has a uniform diameter. 3. DNA is right-handed. 4. The DNA helix has a major groove and a minor groove. 5. Base Pairing in DNA is Complementary. 6. DNA strands are antiparallel. The Double Helical Structure of DNA is Essential to its Function Stores genetic information Susceptible to mutation Precisely replicated Expresses as the phenotype semiconservative dispersive conservative Determining the DNA Replication Mechanism 1958 CIT...
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This note was uploaded on 04/09/2008 for the course BIO 1306 taught by Professor Adair,tamarah during the Spring '08 term at Baylor.

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02 dnastruc - rays by crystals. • Franklin’s photo used...

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