02 dnastruc - rays by crystals • Franklin’s photo used...

Info icon This preview shows pages 1–17. Sign up to view the full content.

View Full Document Right Arrow Icon
Topics for Today: Early Discoveries Science as a social  endeavor. What is the structure of  DNA? How is the structure of  DNA related to the  function of genetic  material? 
Image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Questions for the 1950’s A Paradox to explain: DNA has to copy itself exactly for each cell to function normally and natural selection to be explained. DNA must allow for changes (mutations and recombinations) in order for populations to evolve.
Image of page 2
Rosalind Franklin The Main Characters ..... Francis Crick Cavendish Labs Cambridge (under Bragg) Maurice Wilkins King’s College London (under Randall) James Watson
Image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Related Books and Links A Structure for Deoxyribose Nucleic Acid Nature VOL 171, page737, 1953 The Double Helix by James D. Watson A Reader's Guide to James D.Watson's The Double Helix Rosalind Franklin and DNA by Ann Sayre Science is a social endeavor!
Image of page 4
X-ray crystallography provides clues to the structure of DNA
Image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
The analysis of the scattering or “diffraction” of x-
Image of page 6
Image of page 7

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 8
Image of page 9

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 10
Image of page 11

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 12
Image of page 13

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 14
Image of page 15

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 16
Image of page 17
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: rays by crystals. • Franklin’s photo used to calculate structure of DNA. The Chemical Composition of DNA was known. Chargaff’s Rules: A=T and G=C G C Hydrogen Bonding existed between A and T and G and C Watson and Crick used these clues and model Watson and Crick used these clues and model building to construct a model of DNA building to construct a model of DNA . DNA is a double helix. . DNA has a uniform diameter. 3. DNA is right-handed. 4. The DNA helix has a major groove and a minor groove. 5. Base Pairing in DNA is Complementary. 6. DNA strands are antiparallel. The Double Helical Structure of DNA is Essential to its Function Stores genetic information Susceptible to mutation Precisely replicated Expresses as the phenotype semiconservative dispersive conservative Determining the DNA Replication Mechanism 1958 CIT...
View Full Document

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern