ProbSet04_Key_brief

ProbSet04_Key_brief - BIO 40 Problems Problem Set 4 1. a)...

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BIO 40 Problems Pomona College 1 Problem Set 4 1. a) 45 b) 46 c) d) 2. Mom contributed the X cb ; thus dad failed to contribute a sex chromosome & NDJ in dad. 3. ABCFE*DGH — pericentric inversion ABCD*EFEFGH — duplication ABCD*EFFEGH — duplication and paracentric inversion of the duplicated region ABC*EFGH — deletion
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BIO 40 Problems Pomona College 2 4. a) pericentric inversion b) All 4 “Normal” — 2 with inversion / 2 without 5. a) 4 complementation groups, corresponding to genes, are: mutant 1 mutants 2 and 3 mutants 4,5,6, and 7 mutants 8,9,and 10 b) Anthranilate CDRP InGP Indole Tryptophan blocked: mut 9 mut 1 muts 6 mut 2 c) Could: i) assay for enzymes that catalyze the step that appears blocked, compared to wild type activity for the enzyme. ii) use a physical technique such as NMR or mass spec to ID the accumulated product. iii) Perform “rescue” experiments with the four precursors (e.g., Indole would be predicted to support growth of all but mut 2)
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This note was uploaded on 04/07/2008 for the course BIOL 40 taught by Professor Seligman during the Spring '08 term at Claremont.

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ProbSet04_Key_brief - BIO 40 Problems Problem Set 4 1. a)...

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