Table of Cardiovascular Drugs in Special Populations DrugPregnancy CategoryPediatric Indications ACE INHIBITORS BenazeprilD ≥ 6 years of age; not recommended in children with a glomerular filtration rate less than 30 mL/min/1.73 m(2) (hypertension) CaptoprilC -1st; D 2ndand 3rd Safety and efficacy have not been established in pediatric patients EnalaprilC -1st; D 2ndand 3rdNeonates, infants and children (heart failure and hypertension) FosinoprilC -1st; D 2ndand 3rd ≥ 6 years of age (hypertension) LisinoprilC -1st; D 2ndand 3rd ≥ 6 years of age; not recommended in children with a glomerular filtration rate less than 30 mL/min/1.73 m(2) [hypertension] MoexiprilD Safety and efficacy have not been established in pediatric patients PerindoprilDSafety and efficacy have not been established in pediatric patients QuinaprilC -1st; D 2ndand 3rdSafety and efficacy have not been established in pediatric patients RamiprilC -1st; D 2ndand 3rdSafety and efficacy have not been established in pediatric patients TrandolaprilD Safety and efficacy have not been established in pediatric patients ADRENERGIC NEURON BLOCKERS ReserpineCAvoid use due to the potential for adverse effects (e.g., depression, sedation) and the availability of safer antihypertensive agents. ALPHA 1 BLOCKERS DoxazosinCSafety and efficacy have not been established in pediatric patients PrazosinCOff-label use (hypertension) TerazosinCSafety and efficacy have not been established in pediatric patients ALPHA 2 ADRENERGIC AGONISTS Alpha-methyldopaBNeonates, infants and children (hypertension) ClonidineCOff-label use (hypertension) GuanfacineBSafety and efficacy have not been established in pediatric patients ANTI-THROMBOTIC DRUGS Antiplatelets AspirinNot assigned (OTC)
