Ch17_LO - CH369:LearningOutcomes Chapter17 171...

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CH 369: Learning Outcomes Chapter 17 17-1: Know the 3 sources of fatty acids (dietary, liver, adipocytes) Know the general processes which contribute to atherosclerosis Know the 5 types of lipoproteins o Chylomicrons, VLDL, IDL, LDL, HDL o Know their relative densities (NOT specific values) o Know the general functions of proteins in these particles Make particles soluble Means of binding to cell-surface transporters o Know the general route of transport of these particles o Know that fatty acids (FA) in bloodstream bound to albumin b-oxidation o Know that lipases release FA from triacylglycerols (TAGs) o Know the process of fatty acid activation and the cost in ATP-equivalents What makes this energetically feasible? o Know how FA get transported into mitochondrial matrix and why o Know the net products of each round – type and number of molecules Includes knowing that acetyl-CoA released with each round  o
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