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1Lecture 13Lecture 13Read: BBOM 11e Sec. 5.16, 6.1, 6.3, 17.28•Central Metabolites •Biosynthesis of C and N Compounds•Nitrogen metabolism•Nitrogen metabolism•Peptidoglycan Synthesis•Peptidoglycan Synthesis•Start Bacterial growth•Start Bacterial growthCentral MetabolitesCentral MetabolitesThere are 12 (or 13) central metabolites (intermediate compounds) from which the monomers of macromolecules are synthesized.fructose-6-PO4ribose-5-PO4erythrose-4-PO4Polysaccharidesglycogen, starchDeoxyribose& ribose for nucleic acids,Vitamins and cofactorsAmino acidsfor proteinsGlycerol for lipidsFatty acids for lipidsHeme proteinsFrom E.colito elephants—Biosynthetic pathwaysare very similar!!!NAG, NAM for peptidoglycanLPSSedoheptulose-7 PO4
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