Lecture #13 - Lecture 13 Biosynthesis of C and N Compounds...

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1 Lecture 13 Lecture 13 Read: BBOM 11e Sec. 5.16, 6.1, 6.3, 17.28 Central Metabolites Central Metabolites Biosynthesis of C and N Compounds Biosynthesis of C and N Compounds Nitrogen metabolism Nitrogen metabolism Peptidoglycan Synthesis Peptidoglycan Synthesis Start Bacterial growth Start Bacterial growth Central Metabolites Central Metabolites There are 12 (or 13) central metabolites (intermediate compounds) from which the monomers of macromolecules are synthesized. fructose-6-PO4 ribose-5-PO4 erythrose-4-PO4 Polysaccharides glycogen, starch Deoxyribose & ribose for nucleic acids, Vitamins and cofactors Amino acids for proteins Glycerol for lipids Fatty acids for lipids Heme proteins From E.coli to elephants— Biosynthetic pathways are very similar!!! NAG, NAM for peptidoglycan LPS Sedoheptulose-7 PO4
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2 Peptidoglycan Synthesis Peptidoglycan Synthesis BBOM 11e Fig.6.5 More on Biosynthesis More on Biosynthesis BBOM 11e Sec. 5.15-5.17 Sugars Æ polysaccharides Nucleotides Æ nucleic acids Fatty acids Æ lipids BBOM 11e Sec. 30.1, 30.2, 12.24 Antibiotics and other secondary metabolites of industrial importance BBOM 11e Chapter 7- DNA, RNA, and Protein Synthesis Lectures 20 - 22 BBOM 11e Sec 6.3 Peptidoglycan Synthesis
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This note was uploaded on 02/13/2008 for the course BIO 2900 taught by Professor Ghiorse during the Fall '07 term at Cornell University (Engineering School).

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Lecture #13 - Lecture 13 Biosynthesis of C and N Compounds...

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