Lecture 1 things to know

Lecture 1 things to know - Lecture 1 Energy conserving...

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Lecture 1 Energy conserving products from each of the major catabolic pathways Glycolysis: ATP and NADH Kreb’s Cycle: GTP, NADH, and FADH2 B-oxidation of fatty acids: NADH, FADH2 Oxidation of a-keto acids (from amino acids): NADH, FADH2 Oxidative phosphorylation (e- transport chain): ATP Photophosphorylation (Z scheme): ATP, NADPH Normal “energy donors” (cofactors) in biosynthesis Usually NADPH Localization in cells and tissues of major anabolic pathways Gluconeogensis: cytosol, liver Fatty acid synthesis: cytosol, liver and mammary gland Glycogen synthesis: cytosol, liver and muscle Starch synthesis: chloroplasts Amino acid synthesis: cytosol Steroid hormones: adrenal cortex, ovaries, and testes, mitochondria? In cytosol [NADPH]/[NADP+] is high In mitochonria [NAD+]/[NADH] is high Common features of anabolic pathways Reductive (NADPH) Divergent- make one thing and many things are made from that thing Regulated- at branch points and reciprocally with catabolism Localized- mostly in cytosol
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This note was uploaded on 04/09/2008 for the course BIOCHEM 508 taught by Professor Wiese during the Spring '08 term at Wisconsin.

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Lecture 1 things to know - Lecture 1 Energy conserving...

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