week 11-13 - c. the translated protein. d. Provide...

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Study Guide for March 24- April 11 Genetics 2008 Dr. Padilla Study Guide for Week 11-12. Use to study for exam 3. Topics: Translation, Protein Structure, Mutagenesis 1. Define the following: a. Peptidyl transferase b. Shine Delgarno c. Kozak sequence d. rRNA e. Ribosome f. Chaperones g. Anticodon h. Frameshift mutation i. Point mutation j. Conditional Mutant k. Tautomeric Shift l. Xeroderma Pigmentosa m. Alkylating Agent 2. Diagram the process of translation. In your answer be sure to state the function of the components required for the process. 3. What are two differences between the process of translation in prokaryotes and eukaryotes. 4. Explain why translation stops when the code UAA, UGA or UAG 5. Diagram a dipeptide. Be sure to correctly draw out two different R groups of your choice. 6. Differentiate between Tertiary protein structure and Quaternary protein structure. 7. Given the DNA sequence below: a. what is the dsDNA sequence b. the mRNA sequence in which this DNA codes for
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Unformatted text preview: c. the translated protein. d. Provide directionality of the transcribed and translated product. (That is, label the 5 and 3 end of the transcribed mRNA and the N-terminus and C-terminus of the translated protein) e. If the 6 th Cytosine was mutated to a thymine residue what would result? f. If the 3 rd and 4 th Adenines were deleted what would result? g. If a Guanine was inserted after the 6 th Adenine what would result? h. Name a molecule that can cause what is described in f and g above? 5 a gga gga atg acc gat gac cca gag caa att gag gcc taa gga 3 8. Explain what a thymine dimer is, what causes them, and two mechanisms that living systems have evolved to remove them from DNA. 9. Compare the processes of Base excision repair and Nucleotide excision repair. 10. List 5 cellular changes associated with carcinogens in cigarettes....
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