dna - BY 1116 Biological Sciences I Dr. Kathryn Ponnock...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
BY 1116 Biological Sciences I Dr. Kathryn Ponnock Week 7 – DNA Structure and Replication I. DNA is the Carrier of Genetic Information A. Frederick Griffith Experiments – 1928 1. Used two strains of pneumococcus bacteria 2. One strain (S) was Smooth, Virulent and Lethal 3. Other strain (R) was Rough, Avirulent and Non-lethal 4. Injected mice with heat-killed virulent S strain and mice did NOT DIE . 5. Injected mice with heat-killed virulent S strain and live avirulent R strains – High proportion of mice DIED 6. Griffith isolated living S strain cells from mice 7. Postulated that heat had killed the S strain but did not destroy the hereditary material. Somehow this material was transferred into the living R cells. 8. Known as Transformation 9. Transformation was permanently heritable. 2. Avery, MacLeod and McCarty Experiments – 1944 1. Chemically identified Griffith’s Transforming factor as DNA 2. Used living R cells and highly purified DNA from S cells to obtain the same result as Griffith
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Image of page 2
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/09/2008 for the course BIO SCI 1 102 taught by Professor Ponnock during the Fall '07 term at Delaware Valley University .

Page1 / 3

dna - BY 1116 Biological Sciences I Dr. Kathryn Ponnock...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online