{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

biology notes 2 - Exam know 4 tissue types know about...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Exam: know 4 tissue types, know about epithelial, know what’s in the connective tissue class Mutations – bad changes Nucleotide substitutions (base pair substitutions) Mis-sense Mutation - 1 nucelotide - Causes 1 amino acid to be changed Ex: DNA – GGACTCCTCTTC RNA – CCUGAGGAGAAG Protein – pro-glu-glu-lys *change 5th base in DNA to A *RNA changes, GAG to GUG *amino acid was glu, now val Nonsense Mutations - 1 nucleotide changes in DNA - That changes 1 nucleotide in RNA - Creates a stop codon where there was a codon for an amino acid Addition/Deletion - Can be 1 nucleotide or several - Results in a Frameshift Mutation Reading frame of codons is changed THE BIG RAT ATE THE PIE Insert an S in the sentences o THE BSI GRA TAT ETH EPI E Multiple amino acids are changed Triplet Expansion - Mutation that results in a n increased number of trinucleotide repeats o 3 nucleotides, repeated over and over within a gene Ex: HUNTINGTON DISEASE
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
CAG repeats Normal 6-37 Disease 35-121 Causes of Mutation - Larger genes more likely to mutate - Genes with trinucleotide repeats - CAG Huntington - CGG Fragile X - GC rich genes Radiation- X-rays o Penetrate tissue o
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}