Lecture 2 - What is Disease? Biology of Cancer and AIDS...

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What is Disease? Biology of Cancer and AIDS
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Disease Defined ± Disease: an abnormal condition of an organism that impairs bodily functions. ± In humans, "disease" has a broad use. Refers to any condition that causes discomfort , dysfunction, distress , social problems , and/or death to the person afflicted, or similar problems for those in contact with the person. ± Disease can include injuries , disabilities , disorders , syndromes , infections , isolated symptoms , deviant behaviors , and atypical variations of structure and function .
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Types of Diseases ± Infectious Disease - Pathogen-mediated - Specific organism or combination of organisms ± Genetic Disease - disease caused by abnormalities in an individual’s genetic material (genome) eg. Klinefelter's syndrome , Down’s syndrome , Turner Syndrome ± Environmental disease -Mo lds - Cigarette smoke - Radon - Lead poisoning
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The Cell Theory ± Aristotle : Living things can come from nonliving things = spontaneous generation. ± Jean Baptist Van Helmont (1580-1640): mice come from dirty rags/ rotting grains ± Francisco Redi (1620-1690): challenged the idea of spontaneous generation, setting up the 'meat/maggot' experiment. ± Anton van Leeuwenhoek (1632-1723): first person to make ± Robert Hooke (1630-1703): first person to design a ± Louis Pasteur
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This note was uploaded on 04/08/2008 for the course MICROBIO 160 taught by Professor Hamilton during the Spring '08 term at UMass (Amherst).

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Lecture 2 - What is Disease? Biology of Cancer and AIDS...

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