LECTURE 15 - Biology of Cancer and AIDS Lecture 15:...

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Lecture 15: Lifestyle and Colorectal Cancer Biology of Cancer and AIDS
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Colorectal Cancer Colon cancer is cancer of the large intestine (colon), the lower part of your digestive system. Rectal cancer is cancer of the last 8 to 10 inches of the colon. Together, they are often referred to as colorectal cancers, and they make up the second-leading cause of cancer-related deaths in the United States. http://health.yahoo.com/topic/other/other/article/mayoclinic/13D504C5-40A0-40DA-9F61138EEAAE162F
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The Colorectal Cancer Problem Colorectal cancer is the second leading cause of cancer-related deaths in the United States Cancer of the large intestine accounts for 21% of all cancers in the US Potentially one of the most curable of gastrointestinal cancers Estimated new cases and deaths from colon and rectal cancer in the United States in 2007: New cases: 112,340 (colon); 41,420 (rectal) Deaths: 52,180 (colon and rectal combined) Causes 655,000 deaths worldwide per year.
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Geographic Distribution of Sporadic Colon Cancer There is great variability in the worldwide incidence and mortality rates of colon cancer. Industrialized nations appear to have the greatest risk while most developing nations have lower rates. North America, Western Europe, Australia and New Zealand have high rates for colorectal neoplasms http://hopkins-gi.nts.jhu.edu/pages/latin/templates/index.cfm?pg=disease5&organ=6&disease=36&lang_id=1
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Geographical Relative Survival of Colon and Rectal Cancer http://www.studentbmj.com/issues/00/12/education/452.php
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http://www.patient.co.uk/showdoc/27000573 / Getting to Know Your Gut
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Colon Architecture The colon is what we commonly call the last six feet of the intestines, leading from the small intestine to the rectum The colon is sometimes referred to as the large intestine. Colon or colorectal cancer (terms that can be used interchangeably) is a cancer of the cells lining the colon. Almost all cases of colorectal cancer begin with the development of benign (non- cancerous) polyps http://hopkins-gi.nts.jhu.edu/pages/latin/templates/index.cfm?pg=disease1&disease=36&organ=6&lang_id=1
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Progression of Colon Cancer Begins with the development of
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This note was uploaded on 04/08/2008 for the course MICROBIO 160 taught by Professor Hamilton during the Spring '08 term at UMass (Amherst).

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LECTURE 15 - Biology of Cancer and AIDS Lecture 15:...

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