LECTURE 18 - Lecture 18:Breast Cancer Hormones & Genes...

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Unformatted text preview: Lecture 18:Breast Cancer Hormones & Genes Biology of Cancer and AIDS Breast Cancer • US women have a 1 in 8 chance of developing breast cancer in their lifetime • Second most common cause of cancer death in US • Worldwide, breast cancer is the 2 nd most common cancer • Society for Women’s Health Research showed in 2005 that women feared breast cancer more than heart disease • Openness about having breast cancer, detection and treatment is relatively new http://www.cancer.gov/cancerinfo/pdq/treatment/breast/patient Anatomy of the Breast/ Breast Cancer http://bcancer.com/breast-cancer-blog/index.php?mode=viewid&post_id=309 Noninvasive Breast Cancer Ductal carcinoma in situ (DCIS) cancer cells in the lining of the duct non-invasive, early cancer if left untreated, it may progress to an invasive, infiltrating ductal breast cancer. Lobular carcinoma in situ ( LCIS) noninvasive a marker for an increased risk of invasive cancer in both breasts. According to a 2001 report, for patients with LCIS, the risk for developing invasive cancer in the same breast is about 18% and 14% in the other breast -- after 20 years. These invasive cancers can be either lobular or ductal. Invasive Breast Cancer Invasive Ductal Carcinoma (IDC): penetrates the wall of a duct 70 - 80% of all breast cancer cases Invasive Lobular Carcinoma (ILC): has spread through the wall of a lobule 10 - 15% of all breast cancers It may sometimes appear in both breasts, sometimes in several separate locations Estimated new cases and deaths from breast cancer in the United States in 2007: New cases : 178,480 (female); 2,030 (male) Deaths : 40,460 (female); 450 (male) Time Line of Breast Cancer http://en.wikipedia.org/wiki/Breast_cancer Some Symptoms of Breast Cancer?...
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This note was uploaded on 04/08/2008 for the course MICROBIO 160 taught by Professor Hamilton during the Spring '08 term at UMass (Amherst).

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LECTURE 18 - Lecture 18:Breast Cancer Hormones & Genes...

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