L22-Learning - synapse; the CS starts a weak synapse....

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Cellular Mechanisms of Learning Classical Conditioning o Ivan Pavlov Unconditioned response: food makes dog salivate Before conditioning: Tuning fork (neutral stimulus) brings no conditioned response During condition: pairing tuning fork and food brings unconditioned response After conditioning: Tuning fork brings conditioned response o John Watson “Little Albert” Associated rat (neutral stimulus) with Loud Noise (unconditioned response); result was the sight of the rat brought crying (conditioned response) Cellular Mechanisms of Classical Conditioning o Hypothetical Circuit: Unconditioned response of food delivery signals neuron in somatosensory system; Conditioned response of 1000 Hz signals neuron in the auditory system. The US signal starts a strong
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Unformatted text preview: synapse; the CS starts a weak synapse. Together, the two signals cause salivation • Strengthening Synapses o Donald O. Hebb Activity between presynaptic terminal and postsynaptic neuron strengthens the connection between them “Neurons that fire together, wire together.” o Long term potentiation (LTP) Long term increase in neuronal excitability in response to a particular presynaptic input • The Hippocampus o Perforant path sent to the Dentate gyrus; synapse at the granule cell; sent to the area of the hippocampus called the CA3; synapse at the CA3 pyramidal cell; sent to the CA1 and synapses at the CA1 pyramidal cell; sent out of the hippocampus o EPSP by stimulation of Schaffer collaterals (LTP)...
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This note was uploaded on 04/09/2008 for the course PSYC 220 taught by Professor Brunges during the Spring '07 term at UVA.

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