One-Carbon Metabolism

One-Carbon Metabolism - C H A P T E R 21 ONE-CARBON...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
233 C H A P T E R 21 ONE-CARBON METABOLISM One-Carbon Metabolism Oxidation States of Carbon (See Fig. 21-1.) OXIDATION STATES OF CARBON Count the number of carbons and hydrogens connected to the car- bon in question. Carbon–carbon double bonds count only once. The lower the number, the more oxidized the carbon. Conversions between levels require oxidizing or reducing agents. Conversions within a given level require no oxidizing or reducing agents. ONE-CARBON METABOLISM Function: To donate methyl groups to phospholipid, biogenic amines, thymidine, and amino acid biosynthesis To provide one-carbon fragments at the level of formaldehyde and formic acid for purine and pyrimidine biosynthesis Location: Most everywhere Connections: One-carbon fragments in from serine, glycine, for- mate, and histidine One-carbon fragments out from SAM, formyl-THF, methylene- THF, and methyl-THF Regulation: At individual enzyme level
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
234 Basic Concepts in Biochemistry Determining the oxidation state of a specific carbon atom is simple. Just count the number of carbon and hydrogen atoms that the carbon
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/09/2008 for the course BIO SCI 98 taught by Professor Goulding during the Spring '08 term at UC Irvine.

Page1 / 3

One-Carbon Metabolism - C H A P T E R 21 ONE-CARBON...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online