Apply twice a day Do not exceed 200 gmweek for Advanced

Apply twice a day do not exceed 200 gmweek for

This preview shows page 14 - 23 out of 40 pages.

Apply twice a day. Do not exceed 200 gm/week.
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Psoriasis: Rational Drug Selection (cont d) Treatments prescribed by specialists Phototherapy Systemic medications Methotrexate Oral retinoids Immunosuppressants Tumor necrosis factor blockers
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Psoriasis (cont d) Monitoring Monitor for effectiveness and adverse effects. Outcome evaluation Psoriasis lesions should clear. Patient education Proper application of medications Many medications stain clothes and skin. Some medications cause photosensitivity.
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Acne Pathophysiology Genetic susceptibility Increased sebum production Propionibacterium acnes colonize the follicles and convert the triglycerides in the sebum into free fatty acids. Free fatty acids cause inflammation. Goals of treatment Control acne and keep visible lesions and medication adverse effects to a minimum
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Acne: Rational Drug Selection (cont d) Topical antibiotics Control acne by their bacteriostatic or bactericidal activity against P. acnes Benzoyl peroxide is available OTC. Erythromycin Clindamycin Tetracycline Combination products with benzoyl peroxide and erythromycin or clindamycin
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Acne: Rational Drug Selection (cont d) Oral agents Oral antibiotics Treats the P. acnes colonization Tetracycline, doxycycline, minocycline, erythromycin Hormonal therapy: oral contraceptives Controls the inflammatory component of acne Retinoid: isotretinoin Reserved for severe recalcitrant cystic acne Prescribed by dermatologist Pregnancy category X, requires iPledge registration to confirm pregnancy prevention plan Liver enzyme and lipid levels need to be monitored.
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company Acne Rosacea Affects middle-aged patients Chronic inflammatory disorder of the blood vessels and pilosebaceous glands of the face Treatment Topical metronidazole (Metro-Gel, Noritate) Treatment continues for life.
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Pharmacotherapeutics for Advanced Nurse Practitioner Prescribers, 4th Edition Copyright © 2016 F.A. Davis Company
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