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11.activity. The patient is being treated withgabapentin (Neurontin). After administeringthe medication, the nurse should assess thepatient because of the potential for whatadverse effect?A)TetanyB)HypersensitivityC)Paradoxical seizuresD)CNS depressionAns:DFeedback:The most common adverse effects ofgabapentin are associated with CNSdepression and include dizziness,somnolence, insomnia, and ataxia. The drughas not been noted to cause tetany,hypersensitivity reactions, or paradoxicalseizures.12.A patient with impaired liver function issuffering from a seizure disorder that mostoften results in partial seizures. Which of thefollowing AEDs may be administered to apatient with impaired liver function?A)Oxcarbazepine (Trileptal)B)Fosphenytoin (Cerebyx)C)Carbamazepine (Tegretol)D)Levetiracetam (Keppra)Ans:DFeedback:Levetiracetam (Keppra) is not primarilymetabolized in the liver. Oxcarbazepine(Trileptal) is metabolized in the liver.Fosphenytoin (Cerebyx) is metabolized in theliver. Carbamazepine (Tegretol) ismetabolized in the liver.13.A patient is admitted to the hospital for severeback spasms and pain. Which of the followingskeletal muscle relaxants will act peripherallyon the muscle itself?A)Cyclobenzaprine (Flexeril)B)Carisoprodol (Soma)C)Methocarbamol (Robaxin)
C)Methocarbamol (Robaxin)D)Dantrolene sodium (Dantrium)Ans:DFeedback:Dantrolene is the only skeletal musclerelaxant that acts peripherally on the muscleitself; it inhibits the release of calcium inskeletal muscle cells, thereby decreasing thestrength of muscle contraction. The otherlisted drugs act centrally.14.A patient is recovering from a stroke and hasdeveloped severe muscle contractions. Whichof the following medications will inhibit therelease of calcium in skeletal muscle cells?A)Dantrolene sodium (Dantrium)B)Baclofen (Lioresal)C)Carisoprodol (Soma)D)Cyclobenzaprine (Flexeril)Ans:AFeedback:Dantrium relieves spasticity by inhibiting therelease of calcium in skeletal muscle cells.Lioresal, Soma, and Flexeril act centrally.15.A patient with multiple sclerosis is admittedto the medical division for treatment of severespasticity. What medication is used to treatspasticity and is administered intrathecally?A)Baclofen (Lioresal)B)Carisoprodol (Soma)C)Diazepam (Valium)D)Dantrolene (Dantrium)Ans:AFeedback:Baclofen is used to treat spasticity in MS and
Baclofen is used to treat spasticity in MS andspinal cord injuries. It can be administeredintrathecally. Carisoprodol is used to relievediscomfort from acute, painfulmusculoskeletal disorders. Diazepam is usedto relieve muscle spasms but not usedintrathecally. Dantrolene is used to treatmalignant hyperthermia but not multiplesclerosis.

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