Resolvation energy desolvation energy na oh 2 6

Info icon This preview shows pages 62–69. Sign up to view the full content.

View Full Document Right Arrow Icon
Resolvation Energy ~ Desolvation Energy Na (OH 2 ) 6 + = hydration shell (6 H 2 O needed to stabilize Na + ) Within the K + Ion Channel only : Resolvation Energy <<< Desolvation Energy **When two K + occupy adjacent sites, electrostatic repulsion forces them apart. Thus, as a K + enters the selectivity filter from one side, repulsive force from the next K + entering the filter pushes the first ion through the pore and out the other side, namely out of the cell.
Image of page 62

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 63
The Synapse – The Converging Paradigm Of Neuroscience Ligand-gated channels Voltage-gated channels Stryer: Biochemistry, Third Ed. © 1988, W.H. Freeman & Co. Nature 440 :440-447 (2006) Hartshorne, et al. PNAS 82:240-244 (1985) Nelson, et al. PNAS 77:3057-3061 (1980)
Image of page 64

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 65