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E arteriosclerosis is a disease characterized by

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E.Arteriosclerosis is a disease characterized by increased peripheral resistance, and thusthe heart must generate a larger pressure to move the blood. This leads tohypertension, best indicated by an increase in systolic pressure (PS).
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2. Multiple Choice (20 points, 4 points each)Read each question carefully and write the most appropriate answer in the space provided___d___A. Preload of the left ventricle is affected by which of the following:
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a.there is net filtration out of the capillary and into the tissueb.osmotic pressure favors filtration of fluid out of the capillaryc.there are clefts between endothelial cells that allow for the transport oflarge solutes (i.e. proteins < 7 nm).d.net oxygen transport from the capillary into the tissuee.none of the aboveC. What is the primary role of pre-capillary sphincters?___a___B. Which of the following is true for BOTH pulmonary AND tissue capillaries:
___e___D. Starling’s Law states that fluid filtration rate out of a tissue capillary isDIRECTLY PROPORTIONALto which of the following:
___d__E. An atrioventricular (AV) block is a disease that can be characterized by whichof the following:
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3. Perfusion of a systemic capillary (25 points)In class we assessed the rate of gas diffusion into (oxygen) or out of (carbon dioxide) apulmonary capillary and compared to the rate of blood perfusion. We found that both gaseswere perfusion-limited (many passengers, not enough trains). Let’s now see what conditionsexist in a systemic capillary.A.(8 points) Using the diagram above, perform a similar steady-state mass balance on thecapillary to obtain a differential equation for Pc,O2. As before, use the diffusing capacityto account for diffusion across the capillary membrane (call it DT,O2for this problem).Ignore filtration through any clefts for now.B.

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