CVI and DVT (trauma, intravenous medications) [Hue12]. The buildup of clotting factors and platelets near a venous valve lead to the formation of a thrombus in the vein. The thrombus grows because inflammation surrounding the thrombus stimulates additional platelet aggregation. Pain, redness, and edema to the extremity may occur depending on the significance of the obstruction. Venous thrombi are more prevalent than arterial thrombi because flow and pressure are lower in the vein than in the arteries [Hue12]. An arterial thrombus is more severe and life threatening. The venous thrombotic risk is determined by genetics and acquired risk factors. Acquired risk factors include oral contraceptives, surgery, prolonged bed rest, and cancer [Vli]. Arterial thrombotic risk factors are behavioral such as high blood pressure, smoking, unfavorable lipid profile [Vli]. Treatment options differ slightly between the two types of thrombi. A DVT is treated with compression stockings and blood thinner medication (Coumadin, Lovenox, Xarelto) [May141]. Arterial thrombi are treated with anticoagulants (Heparin, Coumadin), antiplatelet drugs (Aspirin, Plavix), and clot busters. Some patients require a bypass, embolectomy, or angioplasty to remove the thrombus [Che16]. Patient Factor Gender is a contributing factor to the diagnosis of CVI or DVT. Women are at greater risk of developing a DVT and chronic venous insufficiency than men. Women are at an increased danger of developing varicose veins, which leads to the development of chronic venous insufficiency. Pregnancy and elevated estrogen can increase the blood’s ability to clot [May141]. “Pregnancy increases the pressure in the veins in your pelvis and legs” [May141]. Most oral contraceptive pills and hormone replacement therapies contain estrogen and progesterone.
CVI and DVT
- Fall '17
- keisha lovence
- Thrombosis, chronic venous insufficiency