Copyright 2017 Wolters Kluwer All Rights Reserved Question Question What is a

Copyright 2017 wolters kluwer all rights reserved

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Copyright © 2017 Wolters Kluwer • All Rights Reserved Question Question What is a contraindication to receiving a fluoroquinolones? A. Over 65 years B. Weight under 100 pounds C. Fluoroquinolones are contraindicated in patients with known allergy to any fluoroquinolone. D. History of cancer
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Answer Answer c. Fluoroquinolones are contraindicated in patients with known allergy to any fluoroquinolone. Rationale: Fluoroquinolones are contraindicated in patients with known allergy to any fluoroquinolone and in pregnant or lactating patients because potential effects on the fetus and infant are not known.
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Penicillins and Penicillinase - Resistant Antibiotics Penicillins and Penicillinase - Resistant Antibiotics First antibiotic introduced for clinical use Common medications- G benzathine ( Bicillin, Permapen ), penicillin G potassium ( Pfizerpen ), penicillin G procaine ( Wycillin ), penicillin V (generic), amoxicillin ( Amoxil, Trimox ), and ampicillin ( Principen )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Penicillins and Penicillinase - Resistant Antibiotics Cont. Penicillins and Penicillinase - Resistant Antibiotics Cont. Bactericidal Indications - Severe infections caused by sensitive organisms and broad spectrum use Actions- Interfere with the ability of susceptible bacteria to build their cell walls Pharmacokinetics- rapidly absorbed from the GI tract, reaching peak levels in 1 hour. excreted unchanged in the urine and enter breast milk
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Penicillins and Penicillinase-Resistant Antibiotics Cont. Penicillins and Penicillinase-Resistant Antibiotics Cont. Contraindications - Allergies to penicillin or cephalosporins, renal disease, use cautiously in patients who are pregnant or lactating Adverse Effects- Most significant GI tract Drug–Drug Interactions- Tetracyclines, parenteral aminoglycosides
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Patients Receiving Penicillins and Penicillinase- Resistant Antibiotics Cont. Receiving Penicillins and Penicillinase- Resistant Antibiotics Cont. Assess: Known allergy to any cephalosporins and penicillins Physical Skin and mucous membranes for any rashes or lesions Culture and sensitivity tests Respiratory status Abdomen and renal function
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Summary: Amoxicillin Prototype Summary: Amoxicillin
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Sulfonamides Sulfonamides Drugs that inhibit folic acid synthesis Most common medications- sulfadiazine (generic) sulfasalazine ( Azulfidine ) cotrimoxazole ( Septra, Bactrim )
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Sulfonamides Cont.
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