01 Fundamental Concepts of Physiology

Cannon 1871 1945 homeostasis the coordinated

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Walter B. Cannon (1871-1945) Homeostasis “The coordinated physiological reactions which maintain most of the steady states of the body are so complex, and are so peculiar to the living organisms, that it has been suggested that a specific designation for these states be employed – Homeostasis .” Examples: Blood Pressure Homeostasis Plasma Glucose Homeotasis Temperature Homeostasis
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Maintenance of Body Temperature is an Example of Homeostasis
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Body Temperature Homeostasis
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Example: Regulation of Blood Glucose Homeostasis by Pancreatic Hormones - Glucagon and Insulin
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Homeostasis can be Oscillatory e.g. Circadian Rhythm of Body Temperature
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General Principles of Physiology A. Exchange B. Communication C. Mechanism (how things work) D. Control and Regulation
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A. Exchange (e.g. Cardiovascular and Respiratory System) Exchange with the Environment (e.g. Respiratory System) Exchange Within the Body (Long Distance) : Cardiovascular System Exchange Within the Body (Short Distance ): Diffusion
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Balance Diagram for Exchange Between Body and Environment
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Major Organ Systems in the Human Body Cells and Tissues Nervous System Cardiovascular System CO2 O2
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