Explain the difference between the transmission of autosomal and sex linked

Explain the difference between the transmission of

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4.Explain the difference between the transmission of autosomal and sex linked genetic diseases. 5. Use a Punnett Square to predict the chance of the transmission of an autosomal dominant disorder, an autosomal recessive disorder and a sex-linked disorder. 9
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N5315 Advanced Pathophysiology Genetics Core Concepts and Objectives with Advanced Organizers D D d Dd Dd d Dd Dd Autosomal dominate disorder Neither disorder will be expressed in the phenotype. In Autosomal dominant disorders, both alleles must be affected. 100% chance of being a carrier of both Autosomal recessive disorder Neither disorder will be expressed in the phenotype. In Autosomal recessive disorders, both alleles must be affected 100% change of being a carrier of both Sex-linked disorder X Y x xX xY xh Xxh Yxh 25% chance of having disease 50% chance of carrying disease Sex-linked always represented by recessive allele Usually only expressed in men Women have 2 X chromosomes, healthy allele will compensate for diseased allele 10
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  • Fall '15
  • david,mary

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