(Stahl, 2014.). For the treatment of the 8-year-old child dosing should start at 5 mg once
or twice per day, titrating up 5 mg per week for a maximum dose 40mg per day.
Important pharmacokinetics children age 6-12 the half-life for d-amphetamine is 9 hours
and l-amphetamine is 11 hours and these are a mix in both Adderall and Adderall XR in
a ratio of 3:1. The half-life would be important to consider when taking into consideration
dosing for the patient as the patient can have negative effects. Such as insomnia and
weight loss from a decrease in appetite.
Methylphenidate transdermal patch is the medication in the scenario that appears to
have been the most effective in treating the patient’s ADHD symptoms while at school.
The patch should be placed on the hip and rotating sites, not to use the same site every
day. Early removal can be used to stop the medication effect when appropriate. Such as
in the case with the 8-year-old girl, the mother and patient are to remove the patch after
the child returns from school after only 8 out of the 9 hours of wear. This helps with
decreasing the side effects of insomnia and decreased hunger sensation.
Methylphenidate works similarly to Adderall, by blocking the reuptake of dopamine and
norepinephrine. This blockage helps with the symptoms associated with ADHD, such
as, attention, concentration, executive function, and wakefulness in one area of the
brain and hyperactivity in another. Transdermal dosage is 10-30 mg/9 hours and should
be titrated by 5 mg weekly to the effective dose with the least amount of side effects.