E. Most significant client education: teach clients to continue on a low-fat diet and to report any unexplained muscle pain, tenderness, or weakness at once. F. Once a day dosing usually taken in the bedtime. VI. The original anticholesterol prescription drugs were the class known as Bile Acid Sequestrants and are now used as second or third-line therapy for reducing elevated serum cholesterol levels. A. cholestyramine (Questran) B. colestipol (Colestid) C. These drugs are not orally absorbed; they bind to bile acids in the intestine to make them nonreabsorbable, and excreted. The lowered bile acid level prompts cholesterol to be used to make more bile acids. D. Constipation is a common problem and may be accompanied by heartburn, nausea, bloating, and belching. E. Clients should be instructed not to take these drugs at the same time of day as other Drugs. Should dissolve one full minute without stirring and never taken dry just before meals or with meals. 2
VII. Much larger doses of the vitamin B is needed to lower triglycerides, LDL cholesterol, and increases HDL cholesterol than when it is given as a vitamin. A. Side effects are abdominal cramps, pruritus, and GI distress. 1. Small doses of aspirin may be taken 30 minutes before to minimize the flushing. These undesirable effects can also be minimized by starting clients on a low initial dose and increasing it gradually and by having clients take it with meals. VIII. Fibric Acid Derivatives primarily affect the triglyceride levels but may also lower the total cholesterol but may increase or or decrease LDL slightly.
- Winter '16
- ldl cholesterol, ldl cholesterol levels