Questions and Answers 1 Looking at the pedigree discuss three possibilities of

Questions and answers 1 looking at the pedigree

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Questions and Answers 1. Looking at the pedigree, discuss three possibilities of the origin of the hemophilia allele in Queen Victoria. 2. Is there a hemA pedigree that can only be explained by the occurrence of new mutation? 3. You see a family pedigree that has no history of hemophilia on either the mother’s or the father’s side. They have a daughter with hemophilia. Without testing the blood, which type of hemophilia is this most likely to be? (Remember that mutation rates are extremely rare) 4. Look at Queen Victoria’s son Leopold’s family. His daughter, Alice of Athlone, had one hemophilic son (Rupert) and two other children, boy and girl, both normal. What is the probability that Alice of Athlone is a carrier? What is the probability that her daughter is a carrier 5. Victoria’s youngest child, Beatrice gave birth to one daughter, one normal son, and two hemophilic sons. Looking at the pedigree, can you determine if Eugenie is a carrier? Why? 6. Prince Charles is the designated next king of England. His rarriage to Princess Diana produced two sons befor it ended in an acrimonious divorce. If you learned that one of the two sons was a hemophiliac, what are two possible explanations for this event.
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  • Spring '11
  • dr
  • Queen Victoria, Prince Albert, Princess Diana

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