Myeloblast promyelocyte basophilic myelocyte

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>Myeloblast-->Promyelocyte-->Basophilic Myelocyte-->Basophilic Metamyelocyte-- >Basophilic Band-->Basophil Monocyte Maturation Pluripotential Stem Cell-->Myeloid Stem Cell-->CFU-GEMM-->CFU-M-->Monoblast-- >Promonocyte-->Monocyte-->Macrophage Lymphocyte Maturation Pluripotential Stem Cell-->Lymphoid stem cell-> Pre B-->B-Lymphoblast-->B- prolymphocyte-->B-lymphocyte-->Plasma Cell ------------------------------------------------> Pre-T-->T-Lymphoblast-->T-Prolymphocyte-->T Lymphocyte 4. Identfy peripheral blood luekocytes by description only. Neutrophil Band --The nucleus is in a C or S shape, visible chromatin, no nucleoli, coarse clump chromatin, cytoplasm pale blue to pink, primary and secondary granules. Segmented Neutrophil -- Nucleus 2-5 lobes connected by thin filaments w/out visible chromatin, no nucleoli, coarse clumped chromatin, cytoplasm pale blue to pink, primary and secondary granules. Monocyte --Nucleus may be round, horseshoe or kidney shaped. No Nucleoli. Lacy Chromatin, Cytoplasm blue gray and may have psuedopods, many fine granules Eosiniphil --Nucleus 2-3 lobes connect by thin filaments w/out visible chromatin, no nucleoli, chromatin coarse clumped, cytoplasm pink with irregular boarders, primary and secondary granules. Basophil --Nucleus 2 lobes connected by thin filaments w/out visible chromatin, no nucleoli, coarse clumped chromatin, cytoplasm lavender to colorless, few primary granules, lots secondary granules. Lymphocyte --Nucleus is round to oval and may be slightly indented, occasional nucleoli, chromatin condenesed to deeply condensed, cytoplasm skimpy to moderate, sky blue, granules few azurophilic (purple)
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Annemias 1. Explain and calculate red blood cell indices of MCV, MCH, and MCHC. MCV--(Mean Cell Volume is the average volume of the RBC, expressed in femtoliters.) MCV= Hct (%) x 10/ RBC count MCH-- (Mean Cell Hemoglobin is the average weight of Hb in a RBC, expressed in picograms) MCH= Hb (g/dL) x 10/RBC count MCHC--(Mean Cell Hemoglobin Concentration is the average concentration of Hb in each individual erythrocyte. Units used are grams per deciliter.) MCHC= Hb (g/dL) x 100/ Hct(%) 2. Discuss how the reticulocyte count, the corrected reticulocyte count and the reticulocyte production index is used in diagnosing an anemia. Reticulocyte count-- helps divide annemia's into decreased production or shortened RBC survival. (p.221) Corrected Reticulocyte Count and Reticulocyte production index-- better indication of the rate of RBC production. 3. Define the following terms: Anisocytosis-- RBC variation in cell size Poiklocytosis-- RBC variation in cell shape Macrocytosis-- cells are larger than normal RBC's Microcytosis-- Cells are smaller than normal RBC's Normocytic- Normal size RBC's Normochromic--Normal color RBC's Hypochromic--Low color RBC's Polychromasia--will occur if RBC's are low and marrow is pushing immature RBC's out for
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more Oxygen. 4. Describe the various shapes that the red cell can be found in on a peripheral smear using accepted terminology. (pg 222-223) Normal RBC --Normochromic, Normocytic Anisocytosis Macrocytes-- large cells Oval Macrocytes-- large oval cells Microcytes--smaller than normal Poikilocytosis Spherocytes-- Microcytic, no central paller Ovalocytes (elliptocytes)-- oval or eliptical shaped cells
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  • Fall '12
  • professoridon'tknow
  • cells, additional tests, peripheral smear—

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