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28 29 Regulation of Body Metabolism and Temperature

Metabolic effects of cortisol needed for hsl hormone

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Metabolic Effects of Cortisol Needed for HSL (Hormone-Sensitive Lipase) Increases when fasting Deficiency: can lead to hypoglycemia Excess: diabetic-like symptoms Reduces sensitivity of target cells to insulin
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Type I Diabetes Mellitus Insulin-Dependent Primary Cause : Insulin deficiency Hyperglycemia : because glucose uptake and storage are greatly decreased Higher dependence on lipolysis and protein metabolism Glucose appears in the urine : because glucose load exceeds the reabsorptive capabilities of the renal tubules Treatment : Injections of insulin
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Diabetic Ketoacidosis in Type I Diabetes
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Type II Diabetes Insulin Signaling Dysfunction (From: Am. J. Med. 123: S38-S48, 2010)
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Progression of Type 2 Diabetes Mellitus Parallels Declining Beta Cell Function (From: Am. J. Med. 123: S38-S48, 2010)
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Mechanisms of B Cell Failure in Type 2 Diabetes (From: Nature Rev Mol Cell Biol 9: 193-205, 2008)
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Combination Therapy of Type II Diabetes (From: Am. J. Med. 123: S38-S48, 2010)
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Glycemic Index and Glycemic Load (From: American Diabetes Association)
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Glycated Hemoglobin (HbA1C) as an Integrated Measure of Plasma [Glucose] (From: Curr. Opin. Endocrinol, Diabetes Obesity 16: 113-118, 2009)
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(From: Endocrine Practice 15 (6), 2009)
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A1C Versus Glucose Testing (From: Diabetes Care 34: 518-523, 2011) FPG – Fasting Plasma Glucose OGTT – Oral Glucose Tolerance Test A1C – Hemoglobin A1C
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Regulation of Metabolic Rate and Body Temperature
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