Prof John Geddes and others behind eg the Cochrane Collaboration are quite

Prof john geddes and others behind eg the cochrane

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and do not claim to apply to 100% patients. Prof. John Geddes and others behind e.g. the Cochrane Collaboration are quite clear that guidelines should be the first route for evidence-based treatment and probably apply to about 80% patients. That does, however, mean that there will be about 1 in 5 people where evidence-based treatment has been tried and not been successful and where you will need to go beyond any guidelines. Never lose sight of this when dealing with people as individuals. There will be times when you will need to go outside the standard guidelines. Or, to quote NICE themselves: This guidance represents the view of NICE, which was arrived at after careful consideration of the evidence available. Healthcare professionals are expected to take it fully into account when exercising their clinical judgement. However, the guidance does not override the individual responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or guardian or carer, and informed by the summary of product characteristics of any drugs they are considering.
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