Polyvinyl alcohol PVA Propylene glycol Povidone CMC

Polyvinyl alcohol pva propylene glycol povidone cmc

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Polyvinyl alcohol (PVA) Propylene glycol Povidone Carboxymethylcellulose (CMC) Ointments enhanced retention time in the eye compared to artificial tears
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o Active ingredients White petroleum Mineral oil Lanolin o S/E Blurred vision reduce amount, administer before bedtime hypersensitivity reactions preservative-free/non- medicated ointments irritation o Dosing BID may increase if needed Gels--?enhanced retention time in the eye and more tolerated than ointments o Active ingredients Hydroxypropyl methylcellulose 0.3%-->GenTeal Carboxymethylcellulose 1%-->Theratears Gel o Dosing 1-2 drops 3-4x/day PRN Allergic Conjunctivitis o Non-pharmacological Avoiding known triggers Cool compresses Keep doors & windows closed Running AC Using air filters Avoid wearing contacts Wearing sunglasses outside o Pharmacological 1 st line artificial tears 2 nd line topical antihistamines/mast cell stabilizers MOA: antagonizes H1 receptors and stabilizes mast cells to reduce inflammation and allergic reactions Ex: 0.025% ketotifen fumarate Zaditor or Alaway Dosing 1 drop BID every 8-12 hours Other therapies topical decongestants, astringents, or oral antihistamines MOA: causes potent vasoconstriction in the eye to reduce redness Active ingredients: o Phenylephrine o Naphazoline o Tetrahydrozoline o Oxymetazoline S/E: rebound congestion (if used over 72 hours) Dosing 1-2 drops up to 4x/day PRN Decongestants Contraindications o Pt has angle-closure glaucoma
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o Use over 3 days o Naphazoline and tetrahydrozoline less likely to cause rebound preferred Combination antihistamine/decongestant o Pheniramine w/ naphazoline Naphcon-A Opcon-A Visine-A Combination Decongestant/Astringents o C: Zinc sulfate contraction of eye tissue decrease bleeding/danage o w/ naphazoline Clear Eyes ACR o w/phenylephrine Zincfrin Corneal Edema o Non-pharmacological o Pharmacological Hyperosmotic Agents MOA: increase tonicity near the tear film resulting in movement of fluid from cornea to tear film Products: o Sodium Chloride 2% or 5%--> as solutions or ointments Muro 128 Dosing 1-2 gtts q3-4h (ointments less frequent and applied at night) 1 st line NaCl 2% sln 2 nd line NaCl 5% ointment 3 rd line NaCl 5 % solution o Contraindications Compromised or damaged corneal epithelium Loose foreign Object o Pharmacological Ocular Irritants MOA: cleanses surface of the eye and washes away foreign particles Active ingredients: o Sodium Chloride o Sodium Borate o Sodium Phosphate o Potassium Chloride
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