15 explain why linked genes are an exception to the

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15. Explain why linked genes are an exception to the Law of Independent Assortment. What is the exception to that exception? (i.e. how can linked genes still be inherited independently?) 16. Genes A, B, C and D are located on the same chromosome. Given the frequency of recombination below, construct a gene map: between recombo freq between recombo freq A and B 30% A and C 20% B and C 50% B and D 42% C and D 8% A and D 12% 17. Explain why Mendel did not find linkage between seed color and flower color, despite the fact that these genes are on the same chromosome. 18. Distinguish between gene maps, cytogenetic maps and physical maps (p396) in terms of what they include and what differences there may be between them. 19. Describe how sex is genetically determined in humans and explain the significance of the SRY gene. 20. Explain why sex-linked diseases are more common in human males. 21. Describe the inheritance patterns and symptoms of color blindness, Duchenne muscular dystrophy, and hemophilia. 22. Describe the process of X inactivation in female mammals. Explain how this phenomenon produces the tortoiseshell coloration in cats. 23. Explain how nondisjunction can lead to aneuploidy. Define trisomy, triploidy, and polyploidy. Explain how these major chromosomal changes occur and describe possible consequences. 24. Distinguish among deletions, duplications, inversions, and translocations. 25. Define genomic imprinting. Describe the evidence that suggests that the Igf2 gene is maternally imprinted.
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