Patients were either bathed with a control wipe which

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this study 7,727. Patients were either bathed with a control wipe, which was a nonantimicrobial washcloth, or they were bathed with an intervention washcloths which was impregnated with 2% chlorhexidine gluconate. This study was done for 6 months, then the patients were bathed with the alternate product during the next six months. The order in which the patients were assigned to the control or interventions was according to the type of unit and facility. The study was divided into two separate groups. Group 1 started with the CHG washcloths. Group 2 started with the nonantimicrobial washcloths. After the first 6 month periods the groups switched washcloth use for the other. Unfortunately, in June 2008 the CHG wipes experiences a recall. The participating units at this time were removed from the final analysis. During this recall patients were switched to the nonantimicrobial washcloths. The Cox proportional-hazards survival regression model was used. This model compared from the time admission to the first primary bloodstream infection between the control and intervention periods. Additionally, two-sample t-tests and linear regression modeling was used to examine continuous variables, and Fisher's exact test was used to examine categorial variables (Climo et al., 2013). Results of Study Overall, 165 blood stream infections were detected during the control period while only 119 were detected during the intervention period. There were four categories of blood stream infections. These included hospital-acquired, primary bloodstream infection, CLABSI, and secondary bloodstream infection. The study revealed that hospital-acquired bloodstream infections were 119 during the intervention period vs 165 during the control periods. At the time of the intervention period, the cases of CLABSIs were found to be 21 vs 43 during the control
RESEARCH CRITIQUES AND PICOT 9 period. During the intervention periods for secondary blood stream infections and primary bloodstream infections the intervention periods had less infections then the control period. On the basis of the Cox proportional-hazards survival regression analysis, the risk of acquiring a primary bloodstream infection was significantly lower among patients bathed with chlorhexidine than among those bathed with the nonantimicrobial cloths (Climo et al., 2013). There was an accidental finding that CHG wipes have biphasic antifungal activity which showed lower rates of CLABSIs. The overall findings of CLABSIs involving fungal infections were 90% lower during the intervention period that in the control period. CHG has been proven to fight against gram-positive cocci, but there was also findings that CHG reduces fungal infections as well. These findings were not expected. If the results from this study are confirmed that topical usage of chlorhexidine can prevent fungal infections, then the authors reported it could be added to the strategies (Climo et al., 2013). It would be beneficial for nurses to incorporate CHG bathing in many unit settings, especially for patients that have extended ICU stays.

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