PHRM 514 Allergic Rhinitis Fall '12 (2)

1 stimulates irritant receptors 2 pruritus 3 vascular

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1. Stimulates irritant receptors 2. Pruritus 3. Vascular and mucosal permeability 4. Smooth muscle contraction 5. All of the above
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Apgar DA. Allergic Rhinitis. In: Chisholm-Burns MA, Schwinghammer TL, Wells BG, et al., editors. Pharmacotherapy: Principles and Practice. 2nd ed. New York: McGraw Hill Medical; 2010:1047-1049. Rosenwasser L. New insights into the pathophysiology of allergic rhinitis. Allergy Asthma Proc 2007;28:10-15.
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Priming Effect o Results from prolonged or repeated allergen exposure o Easier to stimulate allergic process o Inflamed mucosa becomes hyper-responsive o Smaller doses of allergen or irritants may produce symptoms May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652. Apgar DA. Allergic Rhinitis. In: Chisholm-Burns MA, Schwinghammer TL, Wells BG, et al., editors. Pharmacotherapy: Principles and Practice. 2nd ed. New York: McGraw Hill Medical; 2010:1047-1049.
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What are symptoms of allergic rhinitis?
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Symptoms o Sneezing o Watery or clear rhinorrhea o Nasal congestion o Postnasal drip o Allergic conjunctivitis May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652. Allergic rhinitis. Google Health. Published 2010. Accessed October 10, 2011.
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Limitations to Normal Daily Functions o General fatigue o Mental fatigue o Anxiety o Depressive disorders May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652.
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Other Conditions Associated May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652.
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Complications o Disturbed sleep o Chronic malaise and fatigue o Poor work or school performance o Loss of smell or taste o Postnasal drip with cough, hoarseness, and vocal polyps o A c u t e o t i t i s m e May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652.
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Allergic Salute The allergic salute. ImagesMD. ? ID=ALDIS0212011B&chapID=ALDIS02%2D12&fp=14&tf=83&showstyle=1&pagesize=12&contribid=. Published 2005. Accessed September 2009.
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Allergic Shiners Allergic shiners. Jefferson Clinical Image Database. . Published July 26, 2006. Accessed September 2009.
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Diagnosis o Thorough history o Historical identification of causative allergens o Physical examination (typically more noticeable in children) n Allergic shiners n Transverse nasal crease n Adenoidal breathing n Pale, bluish, edematous nasal turbinates coated with thin, clear secretions n Tearing, periorbital swelling o Nasal scrapings o Allergy testing May JR, Smith PH. Allergic rhinitis. In: DiPiro JT, Talbert RL, Yee GC, et al., editors. Pharmacotherapy a pathophysiologic approach. 8th ed. New York: McGraw Hill Medical; 2011:1649-1652.
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Allergy Testing o Percutaneous (aka skin tests) n Diluted allergen is pricked or scratched into the skin surface n Use a positive control (histamine) and negative control n
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  • Fall '12
  • lipsh
  • Allergic rhinitis, Allergy, McGraw Hill Medical

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