1b. Evolution(1).pdf

Amino acids purines pyrimidines fatty acids thiols

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amino acids, purines, pyrimidines, fatty acids, thiols and a host of other molecular forms may be generated from the input of energy (electrical discharge) Review methods of experimentation (Source of figure 24.4: Campbell 1996) The result If water existed and there was no life, these compounds could have accumulated and exis ted for eons…so these become the foundation on which life is built. The scenarios for the beginning of life Oparin and Haldane o Soup of nutrients is a perfect place for the development of primitive life that was extremely heterotrophic. All the goodies we re there so ‘cells’ only needed the rudiments of metabolic apparatus to make us of them. Eventually the pool ran out forcing development of photosynthesis and intermediary metabolism o Review: Role of heating and cooling, evaporative concentration (think salt from seawater) Most polymerizations are dehydrations (sugar polymerization), so how could much of the advanced polymeric structure arise in an aqueous environment? The issue of concentration: Life began globally or locally? (Banded Iron) Darwins ‘warm - little pond’
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Deamer’s Twist o Extraterrestrial in-fall of material o Ice o Organics: Estimated that in 100 million years an amount of “C” material could enter the aquasphere that exceeded the current crop of C in the biosphere (Source of Figures 2 and 6: Deamer, 1997). See Wachtershouser’s chemistry o Early ‘life’ was autotrophic with an autocatalytic metabolism confined to a 2-dimensional monolayer (NOT CELLULAR at least to begin with) o ‘Organisms’ are bound to positively charged minerals o Surface metabolism requires: Strong surface bonding but must allow lateral movements Substrate must be insoluble but maintain a positive charge (as FeS 2 ) and the surface bonding material should have at least one group with 2 negative charges (-OPO 3 - - , - OP 2 O 6 - - , -OP 3 O 9 - - ) or 2 groups with one negative charge (- COO - , OPO 2
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