blockers , adrenergic antagonists (
prazosin
,
labetalol
), and
theophylline
may be ↑ upon smoking cessation; dose ↓ at
cessation may be necessary.

Trade Name: Rhogam
Classification
: vaccines/immunizing agents
Uses
: Administered to Rho (D)-negative patients who have been
exposed to Rho (D)-positive blood.
Action
: Prevent production of anti-Rho (D) antibodies in Rho
(D)-negative patients who were exposed to Rho (D)-positive
blood.
Contraindications:
Prior hypersensitivity reaction to human
immune globulin; Rho (D)- or Du-positive patients.
Side effects:
DISSEMINATED INTRAVASCULAR
COAGULATION, INTRAVASCULAR HEMOLYSIS, anemia
Nursing implications
: Monitor patient for signs and symptoms
of intravascular hemolysis (IVH) (back pain, shaking chills,
fever, hemoglobinuria), anemia, and renal insufficiency. If
transfusions are required, use Rho (D)-negative packed red blood
cells to prevent exacerbation of IVH.
Dosage
: Following Delivery
IM: (Adults) HyperRHO S/D Full Dose, RhoGAM– 1 vial
standard dose (300 mcg) within 72 hr of delivery.
Before Delivery
IM: (Adults) HyperRHO S/D Full Dose, RhoGAM– 1 vial
standard dose (300 mcg) at 26–28 wk.
Termination of Pregnancy (<13 wk Gestation)
IM: (Adults) HyperRHO S/D Mini-Dose, MICRhoGAM– 1 vial
of microdose (50 mcg) within 72 hr.
Interactions
: May ↓ antibody response to some live-virus
vaccines ( measles , mumps , rubella ).

Trade Name: Rubella Vaccine
Classification
: Vaccine Combinations with Measles/Mumps
Component
Uses
: immunity against measles (rubeola), mumps, and rubella
(German measles)
Action
: Combination of three live virus vaccinations intended to
confer immunity against measles (rubeola), mumps, and rubella
(German measles); commonly used in routine childhood
vaccinations.
Contraindications
: Severe allergy to gelatin
Side effects
: injection site reactions (pain, redness, swelling, or
a lump), fever, irritability, mild swollen glands (lymph nodes),
measles-like rash, hives, tiredness, sore
throat, dizziness, headache, nausea, vomiting, diarrhea, body
aches, cough, runny nose & tiredness
Nursing implications
: assessment of injection site.
Dosage
: 0.5 mL subcutaneously. The Advisory Committee on
Immunization Practices (ACIP) recommends a 2-dose vaccine
schedule during childhood for MMR. For routine immunization,
the recommended schedule is administration of the first dose at
age 12 to 15 months and the second dose at age 4 to 6 years
Interactions
: promotes the production of antibodies for rubella
virus.

Trade Name: Maalox
Classification
: antacids
Uses
: Useful in a variety of GI complaints, including:
Hyperacidity, Indigestion, GERD, Heartburn.
Action
: Neutralize gastric acid following dissolution in gastric
contents.
Contraindications
: Severe abdominal pain of unknown cause,
especially if accompanied by fever
Side effects
: aluminum salts: constipation magnesium salts:
diarrhea
Nursing implications
: To prevent tablets from entering small
intestine in undissolved form, they must be chewed thoroughly
before swallowing. Follow with at least ½ glass of water.
Dosage
: PO: (Adults and Children ≥12 yr): 5–30 mL or 1–2
tablets 1–3 hr after meals and at bedtime.
Interactions
: Absorption of tetracyclines , phenothiazines ,
ketoconazole
,
itraconazole
, iron salts , fluoroquinolones , and
isoniazid
may be ↓ (separate by at least 2 hr).

Trade Name: Pneumococcal Vaccine
Classification
:
Vaccines, Inactivated, Bacterial
Uses
: Indicated for active immunization for the prevention of
pneumococcal disease caused by the 23 serotypes contained in
the vaccine
Action
: Exposes body to live weakened
Contraindications


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- Fall '19