Practice_Midterm_4_–_FALL_2009

Tarceva works by the following mechanism a cleaving

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11.Tarceva works by the following mechanism: a) Cleaving the intracellular portion of EGFR allowing it to be degraded b) Blocking the tyrosine kinase domain of EGFR c) Preventing EGFR dimerization and subsequent phosphorylation of other proteins d) Preventing EGFR ligands from binding and transmitting pro-mitogenic signals e) Inducing apoptosis via ubiquination of NF-kB 12. A drug that was already on the market that was involved in blocking angiogenesis was: 13.Folkman’s search for an “angiogenesis inhibitor” started with
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14.Folkman’s first encounter with Angiogenesis occurred when: 15.The drug that once had been pre-approved that was studied because it blocked angiogenesis was: a)once used as a treatment for morning sickness b)responsible for birth defects in infants in Europe c)Was used as a folic acid supplement d)Used in vaccines e)A & B f)All of the above
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