Explain how phenotypic expression of the heterozygote

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Explain how phenotypic expression of the heterozygote differs with complete dominance, incomplete dominance, and codominance. Provide an example of each inheritance pattern. 8. Explain why Tay-Sachs disease is considered recessive at the organismal level, incompletely dominant at the biochemical level and codominant at the molecular level. 9. Explain why dominant alleles are not necessarily more common in a population. Illustrate your explanation with an example. 10. Describe the inheritance of the ABO blood system and explain how it illustrates both Mendelian inheritance (dominant vs. recessive) and codominance. 11. Define and give examples of pleiotropy , epistasis , and polygenic inheritance . 12. Achondroplasia runs in the Roloff family of Little People, Big World . Both parents have the condition. Of their four kids, one of the eldest twin sons has achondroplasia, but the other does not. Neither the daughter nor the youngest son have the condition. Create a pedigree for the family. If son with achondroplasia has a child with a woman without achondroplasia, what are the
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AP Biology 2 chances that that child will have the condition? Add the woman and the possible child to the pedigree as well. 13. Describe the inheritance and expression of cystic fibrosis, Tay-Sachs disease, Huntingtons disease and sickle-cell disease. 14. Explain how carrier recognition, fetal testing, and newborn screening can be used in genetic screening and counseling.
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