Psy137SexBehavFemale

Menopause during the perimenopausal period up to 10

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Menopause During the perimenopausal period (up to 10 years before menopause), the ovaries decrease production of the "female hormones" estrogen and progesterone, the hormones which allow a woman to become pregnant and to menstruate. The average age for menopause in American women is 51
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Menopause There is a dysregulation of the cyclic nature of release of the HP horomones
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Hormone Replacement Therapy (HRT) Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women (WHI) 1 - 1993-1998 What are the major health benefits and risks of HRT in the U.S. based on a randomized controlled primary prevention trial
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Sex and the Brain Female Very similar to the male system Sensory to Medial amygdala Large olfactory component Connects to MPA and also the Ventromedial nucleus of hypothalamus (VMH) VMH and MPA connect to the PAG and then to the nPGi in the medulla and down to motor neurons in the lumbar region of the spinal cord FMRI data from women achieving orgasm via manual stimulation show similar brain regions to men active basal forebrain, basal ganglia, cerbellum, and PAG
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Fos in primate females after copulation. Procedure: Mated for 60 min (2-3 ejaculation) Return to home cage Sacrifice 60 min later; therefore hard to tell what has induce c-Fos. Michael et al 2005 Physiology & Behaivor 85(4) 404-413
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Experience, Dopamine and Female sex behavior. Experience enhances dopamine increases in the NAC during copulation. Reviewed in Meisel et al 2006 VTA N.Acc DA
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Areas of significant BOLD signal increases in female subjects when brain activation associated with viewing the emotionally neutral film excerpts were subtracted from that associated with viewing the erotic film excerpts . A: Medial prefrontal cortex, anterior cingulate cortex, thalamus and hypothalamus. B: Orbitofrontal cortex. C: Insular cortex. D: Amygdala. E: Ventral striatum. F: Occipitotemporal cortex. Karama et al 2002 Hum Brain Mapp. 16(1):1-13 FMRI and Sexual imagery: Women
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Male versus Females Major difference was in thalamus and hypothalamus.
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Menopause During the perimenopausal period up to 10 years...

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