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Merocrine glands are synthesized on ribosomes

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merocrine glands are synthesized on ribosomesattached to rough ER; processed, sorted, and packaged by the Golgi complex; and released fromthe cell in secretory vesicles via exocytosis. EX: salivary glands and pancreas.Apocrine glandsaccumulate their secretory product at the apical surface of the secreting cell. Then, that portion ofthe cell pinches off by exocytosis from the rest of the cell to release the secretion. The cellrepairs itself and repeats the process. EX: secretion of milk fats in the mammary glands. Thecells ofholocrine glands accumulate a secretory product in their cytosol. As the secretory cellmatures, it ruptures and becomes the secretory product. EX: sebaceous gland of the skin.Connective tissueVariety of functions: binds together, supports and strengthens other body tissues; protects andinsulates internal organs; compartmentalizes structures such as skeletal muscles; serves as themajor transport system within the body, is the primary location of stored energy reserves(adipose); and is the main source of immune responseTwo basic elements:extracellular matrix and cells. Extracellular matrix consists of protein fibresand ground substance. Fibres are secreted by connective tissue cells, account for functionalproperties of the tissue, and control surrounding watery environment via specificproteoglycanmolecules.Exception to connective tissue being vascular: cartilage and tendonsConnective tissue cells:Embryonic cells calledmesenchymal cells give rise to cells of connective tissue. Each type ofconnective tissue contains an immature class of cells (blast cells). Blast cells retain the capacityfor cell division and secrete the extracellular matrix that is characteristic of the tissue. In cartilageand bone, once the extracellular matrix is produced, the immature cells differentiate into mature
cells with names ending in -cyte, which have reduced capacities for cell division andextracellular matrix formation and are mostly involved in monitoring and maintaining theextracellular matrix.-Fibroblasts: large, flat cells with branching. Present in all general connective tissues, numerous.Migrate through connective tissues, secreting the fibres and certain components of the groundsubstance.-Macrophages: develop from monocytes (WBC), irregular shape with short branching,Fixedmacrophages reside in a particular tissue (alveolar macrophages).Wandering macrophages movethroughout the tissue and gather at sites of infection/inflammation to carry out phagocytosis-Plasma cells: small cells that develop fromB lymphocyte. Secrete antibodies. Mostly reside inconnective tissue especially in GI and respiratory tracts.-Mast cells: abundant alongside blood vessels that supply connective tissue. Produce histamine(dilates small blood vessels) in response to injury/injection.

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