Pesticides health impacts in response to a stimulus

Info icon This preview shows pages 67–78. Sign up to view the full content.

View Full Document Right Arrow Icon
Pesticides: Health Impacts In response to a stimulus, endocrine glands  release hormones   to carry instructions to specific cells These chemical messengers travel from  head to toe or just to the cell next door  looking for and locking onto special binding  proteins, known as receptors, that are  located in and on the  target cells The endocrine system response
Image of page 67

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Pesticides: Health Impacts Once bound, the receptor reads the  hormone's message and carries out its  instructions by starting one of two  distinct cellular processes: The endocrine system response
Image of page 68
Pesticides: Health Impacts A) turn on genes to make new proteins,  which causes long-term effects such as  the release of growth hormones or  sex steroid hormones B) alter the activity of existing cellular  proteins, which produce rapid responses  such as faster heart beat or  varied sugar blood levels The endocrine system response
Image of page 69

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Pesticides: Health Impacts The endocrine system response Steroid entering a cell, binding a receptor, binding  to DNA, and initiating genetic transcription 
Image of page 70
Pesticides: Health Impacts Pesticides and the endocrine response Certain substances can mimic hormones by binding  to specific hormone receptors inside cells
Image of page 71

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Pesticides: Health Impacts Pesticides and the endocrine response There is an increasing body of evidence  linking reproductive system abnormalities  (reduced sperm motility, sperm defects,  sex reversals and altered sex ratios) with exposure to the synthetic chemicals  known as endocrine disruptors Endocrine disruptors and the  reproductive system
Image of page 72
Image of page 73

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Pesticides: Health Impacts Pesticides and the endocrine response Symptoms have been identified in males of  many species, including birds of prey  around the Great Lakes, alligators in Florida,  harbour seals in the Netherlands,  polar bears in the Arctic Endocrine disruptors and the  reproductive system
Image of page 74
Pesticides: Health Impacts Pesticides and the endocrine response Endocrine disruptors and the  reproductive system These endocrine disruptors include  pesticides and certain industrial chemicals  like dioxin, PCBs, phthalates, arsenic,  lead and mercury Some of these chemicals mimic estrogen,  others interfere with testosterone, and  some block the thyroid function
Image of page 75

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Pesticides: Health Impacts Pesticides and the endocrine response Medical studies have also indicated that the  sperm counts of males in North America and  Europe have decreased over the last 50 years (this decline may be as great as 40%) Endocrine disruptors and the  reproductive system
Image of page 76
Pesticides: Health Impacts Pesticides and the endocrine response Workers exposed to endocrine-disrupting 
Image of page 77

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 78
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern