CHEM 151 study guide for all chapters

What is the association of each of the following

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2. What is the association of each of the following names with strychnine: a) Strychnos ignatii b) Joseph Bienaimé Caventou and Pierre Joseph Pelletier c) Sir Robert Robinson d) R. B. Woodward 3. Provide the structures, including stereochemistry, of coniine, nicotine and cocaine.
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Chapter 13: Penicillin 1. Provide the structure, including stereochemistry, of penicillin V and give the name of its discoverer. 2. Write a short essay (100 words or less) on the impact of the discovery of penicillin on medicine and society.
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3. What is the association of each of the following persons with penicillin? 4. Name the three recipients of the 1945 Nobel Prize in Physiology or Medicine for the penicillin success story. 5. Provide the name and structure of the reagent developed and employed for the construction of the ß-lactam ring of penicillin in the first total synthesis of this antibiotic.
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Chapter 14: Longifolene 1. Briefly describe (100 words or less) what is meant by the term ‘Retrosynthetic Analysis’ in the context of the art of total synthesis, mentioning the famous chemist who developed it, the first molecule to which it was applied, and how this theory has impacted education and research.
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Chapter 15: Prostaglandins and Leukotrienes 1. Provide the structures (with stereochemistry) of four of the following molecules: a) Prostaglandin F 2 α b) Arachidonic acid c) Prostaglandin H 2 d) Thromboxane A 2 e) Prostacyclin f) Leukotriene D 4 2. Describe (50 words or less) the contributions of E. J. Corey to the field of prostaglandins and leukotrienes, and explain how these contributions have impacted biology and medicine.
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3. Name the three recipients of the 1982 Nobel Prize in Physiology or Medicine for discoveries in the prostaglandin and related areas, and mention one specific contribution of each scientist. 4. Mention one biological source, one physiological role, and one medical application derived from research within the prostaglandin field. 5. Mention one biological source, one physiological role, and one medical application derived from research related to the leukotriene field.
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Chapter 16: Vitamin B 12 1. Briefly describe (50 words or less) the contribution of James Lind to the discovery of vitamins. 2. Write the structures (including stereochemistry) of vitamins C, vitamin E ( α - tocopherol), and vitamin B 6 , and state the beneficial function of each to the human body.
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3. Name the contribution to the field of vitamin B 12 of each of the following scientists. 4. Describe briefly (50 words or less) the term ‘Woodward–Hoffmann Rules’.
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Chapter 17: Erythronolide B and Erythromycin A 1. Explain the clinical applications of the erythromycins. 2. Name one discovery or accomplishment within the field of antibiotics for each of the following scientists.
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